At a time when the world is facing the unprecedented challenge of a pandemic and a variety of other pressing global issues, the EU needs to assert a new geopolitical identity and reshape its relations with international players, in particular Africa and China. On the basis of recommendations formulated by a group of distinguished European, African and Chinese experts, this policy paper proposes an EU strategic agenda for cooperation with Africa and China. The ambitious trilateral cooperation strategy is centred around three policy areas: health, economic development, good governance and security.